• 师资队伍


赖国松简介

发布者:化工化学学院发布时间:2022-05-17浏览次数:5222



姓名:赖国松 (Guosong Lai)

职称:教授,楚天学者特聘教授

学历学位:博士

学科专业:分析化学

研究方向:生化分析及生物传感

联系方式:gslai@hbnu.edu.cn

课题组研究室:重点实验室413, 414


个人简介

 赖国松,博士,楚天学者特聘教授,中国化学会高级会员,化学化工学院副院长。2001年本科毕业于湖北师范大学化学专业后留校工作,2008年硕士毕业于华中师范大学分析化学专业,2011年博士毕业于南京大学化学专业,2012年8月至2013年12月于澳大利亚斯维本科技大学从事博士后研究。2011年评为副教授,2015年入选楚天学者计划楚天学子,2016年评为教授,2021年入选楚天学者计划特聘教授。兼任国际期刊Biosensors and Bioelectronics编委、湖北省化学化工学会青年委员会委员及黄石市留学回国人员联谊会理事等职务。

 主要从事分析化学专业教学与生化分析及生物传感方向研究工作。主持国家自然科学基金面上项目、青年项目和湖北省自然科学基金面上项目等近10项科研项目研究。在Analytical Chemistry, Chemical Communications, Biosensors and Bioelectronics, Advanced Functional Materials和Nanoscale等国际刊物上发表SCI收录科研论文100余篇;论文SCI正面引用、评价2700余次,个人H指数30。获国家发明专利授权6项,合著英文学术专著1部。以主要完成人获省部级一、二等科技奖励各1项,以第一完成人获黄石市自然科学优秀学术成果一等奖等其他学术奖励7项。


教学及人才培养

 1. 主讲《分析化学》《分析化学实验》《现代分析化学》等本科生课程

 2. 主讲《电分析化学》《化学进展》等研究生学位课程

 3. 承担本科生学位论文及综合化学实验指导工作

 4. 担任《分析化学》省级精品课程、精品资源共享课程负责人

 5. 担任分析化学学科研究生导师及学科方向负责人


主要科研课题

 1. 主持:国家自然科学基金面上项目(22076043),2021-2024年

 2. 主持:湖北省高等学校优秀中青年科技创新团队计划(T201810),2018-2021年

 3. 主持:湖北师范大学优秀科研创新团队计划(T201501),2015-2017年

 4. 主持:湖北省自然科学基金面上项目(2014CFB279),2015-2016年

 5. 主持:教育部留学回国人员科研启动基金(第49批),2015年

 6. 主持:国家自然科学基金青年项目(21205031),2013-2015年

 7. 参研:国家自然科学基金面上项目(21475033),2015-2018年

 8. 参研:湖北省高等学校优秀中青年科技创新团队(T201311),2013-2016年


代表性论文论著

 1. Haiyan Wang, Yiming Xie, Yujia Wang, Guosong Lai*, Target biorecognition-triggered assembly of a G-quadruplex DNAzyme-decorated nanotree for the convenient and ultrasensitive detection of antibiotic residues, Science of the Total Environment, 2022, 813, 152629(SCI影响因子:7.963)

 2. Wan Huang, Danyan Zhan, Yiming Xie, Xin Li, Guosong Lai*, Dual CHA-mediated high-efficient formation of a tripedal DNA walker for constructing a novel proteinase-free dual-mode biosensing strategy, Biosensors and Bioelectronics, 2022, 197, 113708(SCI影响因子:10.618)

 3. Xin Li*, Haiyan Wang, Xiaojun Wang, Guosong Lai*, Jingming Gong*, “All-in-One” ultra-portable colorimetric sensor coupled with confinement effect for Hg2+ highly sensitive and instant detection, Sensors and Actuators B: Chemical, 2022, 351, 130945(SCI影响因子:7.460)

 4. Wan Huang#, Peng Guo#, Bo Li, Li Fu, Cheng-Te Lin, Aimin Yu, Guosong Lai*, Enzyme-catalyzed deposition of polydopamine for amplifying the signal inhibition to a novel Prussian blue-nanocomposite and ultrasensitive electrochemical immunosensing, Journal of Materials Science and Technology, 2022, 102, 166–173(SCI影响因子:8.067)

 5. Xiaojun Wang, Tingting Xuan, Wan Huang, Xin Li, Guosong Lai*, Endonuclease-driven DNA walking for constructing a novel colorimetric and electrochemical dual-mode biosensing method, Analytica Chimica Acta, 2022, 1208, 339835(SCI影响因子:6.558)

 6. Yiming Xie, Haiyan Wang, Xinyue Yuwen, Guosong Lai*, Exo III-catalyzed release of a Zn2+-ligation DNAzyme to drive the strand displacement reaction and gold aggregation for the homogeneous bioassay of kanamycin antibiotics, Journal of Agricultural and Food Chemistry, 2021, 69, 10371–10378(SCI影响因子:5.279)

 7. Wan Huang, Yue Zhou, Danyan Zhan, Guosong Lai*, Homogeneous biorecognition reaction-induced assembly of DNA nanostructures for ultrasensitive electrochemical detection of kanamycin antibiotic, Analytica Chimica Acta, 2021, 1154, 338317(SCI影响因子:6.558)

 8. Chuanying Qin, Cong Hu, Aimin Yu, Guosong Lai*, Fe3O4@polydopamine and Exo III-assisted homogeneous biorecognition reaction for convenient and ultrasensitive detection of kanamycin antibiotic, Analyst, 2021, 146, 1414–1420(SCI影响因子:4.616)

 9. Xiaolei Cai, Fuhui Lv, Guosong Lai*, Li Fu, Cheng-Te Lin, Aimin Yu*, Dually enhanced homogenous synthesis of molybdophosphate by hybridization chain reaction and enzyme nanotags for the electrochemical bioassay of carcinoembryonic antigen, Microchimica Acta, 2020, 187: 361(SCI影响因子:5.833)

 10. Liling Deng, Guosong Lai*, Li Fu, Cheng-Te Lin, Aimin Yu*, Enzymatic deposition of gold nanoparticles at vertically aligned carbon nanotubes for electrochemical stripping analysis and ultrasensitive immunosensing of carcinoembryonic antigen, Analyst, 2020, 145, 3073–3080(SCI影响因子:4.616)

 11. Yiming Xie, Feina Niu, Aimin Yu, Guosong Lai*, Proximity binding-triggered assembly of two MNAzymes for catalyzed release of G-quadruplex DNAzymes and an ultrasensitive homogeneous bioassay of platelet-derived growth factor, Analytical Chemistry, 2020, 92, 593–598(SCI影响因子:6.986)

 12. Bo Li, Lu Qin, Jie Zhou, Xiaolei Cai, Guosong Lai*, Aimin Yu, Hybridization chain reaction-enhanced enzyme biomineralization for ultrasensitive colorimetric biosensing of a protein biomarker, Analyst, 2019, 144, 5003–5009(SCI影响因子:4.616)

 13. Zhichao Chen, Yiming Xie, Wan Huang, Chuanying Qin, Aimin Yu, Guosong Lai*, Exonuclease-assisted target recycling for ultrasensitive electrochemical detection of microRNA at vertically aligned carbon nanotubes, Nanoscale, 2019, 11, 11262–11269(SCI影响因子:7.790)

 14. Zhichao Chen, Feng Xiong, Aimin Yu, Guosong Lai*, Aptamer biorecognition- triggered DNAzyme liberation and Exo III-assisted target recycling for ultrasensitive homogeneous colorimetric bioassay of kanamycin antibiotic, Chemical Communications, 2019, 55, 3959–3962(SCI影响因子:6.222)

 15. Wan Huang, Hongyu Zhang, Guosong Lai*, Shun Liu, Bo Li, Aimin Yu*, Sensitive and rapid aptasensing of chloramphenicol by colorimetric signal transduction with a DNAzyme-functionalized gold nanoprobe, Food Chemistry, 2019, 270, 287–292(SCI影响因子:7.514)

 16. Peng Guo#, Yun Wang#, Zhichao Chen, Tianqi Jin, Li Fu, Cheng-Te Lin, Guosong Lai*, Voltammetric immunoassay of human IgG based on the release of cadmium(II) from CdS nanocrystals deposited on mesoporous silica nanospheres, Microchimica Acta, 2019, 186, 15(SCI影响因子:5.833)

 17. Zhichao Chen, Guosong Lai*, Shun Liu, Aimin Yu, Ultrasensitive electrochemical aptasensing of kanamycin antibiotic by enzymatic signal amplification with a horseradish peroxidase-functionalized gold nanoprobe, Sensors and Actuators B: Chemical, 2018, 273, 1762–1767(SCI影响因子:7.460)

 18. Bo Li, Guosong Lai*, Bei Lin, Aimin Yu, Nianjun Yang, Enzyme-induced biomineralization of cupric subcarbonate for ultrasensitive colorimetric immunosensing of carcinoembryonic antigen, Sensors and Actuators B: Chemical, 2018, 262, 789–795(SCI影响因子:7.460)

 19. Bo Li, Aimin Yu, Guosong Lai*, Self-assembly of phenoxyl-dextran on electrochemically reduced graphene oxide for nonenzymatic biosensing of glucose, Carbon, 2018, 127, 202–208(SCI影响因子:9.594)

 20. Guosong Lai*, Min Zheng, Wenjie Hu, Aimin Yu*, One-pot loading high-content thionine on polydopamine-functionalized mesoporous silica nanosphere for ultrasensitive electrochemical immunoassay, Biosensors and Bioelectronics, 2017, 95, 15–20(SCI影响因子:10.618)

 21. Shun Liu, Guosong Lai*, Haili Zhang, Aimin Yu*, Amperometric aptasensing of chloramphenicol at a glassy carbon electrode modified with a nanocomposite consisting of graphene and silver nanoparticles, Microchimica Acta, 2017, 184, 1445–1451(SCI影响因子:5.833)

 22. Bo Li, Guosong Lai*, Haili Zhang, Shengli Hu, Aimin Yu, Copper chromogenic reaction based colorimetric immunoassay for rapid and sensitive detection of a tumor biomarker, Analytica Chimica Acta, 2017, 963, 106–111(SCI影响因子:6.558)

 23. Hui Cheng, Lingling Xu, Haili Zhang, Aimin Yu, Guosong Lai*, Enzymatically catalytic signal tracing by a glucose oxidase and ferrocene dually functionalized nanoporous gold nanoprobe for ultrasensitive electrochemical measurement of a tumor biomarker, Analyst, 2016, 141, 4381–4387(SCI影响因子:4.616)

 24. Guosong Lai*, Hui Cheng, Dinghong Xin, Haili Zhang, Aimin Yu, Amplified inhibition of the electrochemical signal of ferrocene by enzyme-functionalized graphene oxide nanoprobe for ultrasensitive immunoassay, Analytica Chimica Acta, 2016, 902, 189–195(SCI影响因子:6.558)

 25. Guosong Lai*, Haili Zhang, Aimin Yu*, Huangxian Ju, In situ deposition of Prussian blue on mesoporous carbon nanosphere for sensitive electrochemical immunoassay, Biosensors and Bioelectronics, 2015, 74, 660–665(SCI影响因子:10.618)

 26. Hui Cheng, Guosong Lai*, Li Fu, Haili Zhang, Aimin Yu, Enzymatically catalytic deposition of gold nanoparticles by glucose oxidase-functionalized gold nanoprobe for ultrasensitive electrochemical immunoassay, Biosensors and Bioelectronics, 2015, 71, 353–358(SCI影响因子:10.618)

 27. Guosong Lai*, Haili Zhang, Tasnuva Tamanna, Aimin Yu*, Ultrasensitive immunoassay based on electrochemical measurement of enzymatically produced polyaniline, Analytical Chemistry, 2014, 86, 1789–1793(SCI影响因子:6.986)

 28. Guosong Lai*, Haili Zhang, Jiawey Yong, Aimin Yu*, In situ deposition of gold nanoparticles on polydopamine functionalized silica nanosphere for ultrasensitive nonenzymatic electrochemical immunoassay, Biosensors and Bioelectronics, 2013, 47, 178–183(SCI影响因子:10.618)

 29. Xiaowen Zhang, Guosong Lai*, Aimin Yu, Haili Zhang*, A glassy carbon electrode modified with a polyaniline doped with silicotungstic acid and carbon nanotubes for the sensitive amperometric determination of ascorbic acid, Microchimica Acta, 2013, 180, 437–443(SCI影响因子:5.833)

 30. Guosong Lai, Lili Wang, Jie Wu, Huangxian Ju*, Feng Yan*, Electrochemical stripping analysis of nanogold label-induced silver deposition for ultrasensitive multiplexed detection of tumor markers, Analytica Chimica Acta, 2012, 721, 1–6(SCI影响因子:6.558)

 31. Guosong Lai, Jie Wu, Huangxian Ju*, Feng Yan*, Streptavidin-functionalized silver-nanoparticle-enriched carbon nanotube tag for ultrasensitive multiplexed detection of tumor markers, Advanced Functional Materials, 2011, 21, 2938–2943(SCI影响因子:18.808)

 32. Guosong Lai, Jie Wu, Chuan Leng, Huangxian Ju*, Feng Yan*, Disposable immunosensor array for ultrasensitive detection of tumor markers using glucose oxidase-functionalized silica nanosphere tags, Biosensors and Bioelectronics, 2011, 26, 3782–3787(SCI影响因子:10.618)

 33. Guosong Lai, Feng Yan, Jie Wu, Chuan Leng, Huangxian Ju*, Ultrasensitive multiplexed immunoassay with electrochemical stripping analysis of silver nanoparticles catalytically deposited by gold nanoparticles and enzymatic reaction, Analytical Chemistry, 2011, 83, 2726–2732(SCI影响因子:6.986)

 34. Guosong Lai, Feng Yan, Huangxian Ju*, Dual signal amplification of glucose oxidase-functionalized nanocomposites as a trace label for ultrasensitive simultaneous multiplexed electrochemical detection of tumor markers, Analytical Chemistry, 2009, 81, 9730–9736(SCI影响因子:6.986)

 35. Huangxian Ju, Guosong Lai, Feng Yan, Immunosensing for Detection of Protein Biomarkers, ELSEVIER, 2017, ISBN: 9780081019993(学术专著)


发明专利

 1. 赖国松, 郭鹏,一种检测氯霉素的均相比色生物分析方法及其应用,专利号:ZL201910345502.0,授权公告日:20210406

 2. 赖国松, 陈志超,一种检测卡那霉素的均相生物传感方法及其应用,专利号:ZL201811099210.5,授权公告日:20210316

 3. 赖国松, 郭鹏,一种基于普鲁士蓝的电化学免疫传感器及基于该传感器所建立的电化学免疫传感方法和应用,专利号:ZL201811311939.4,授权公告日:20210126

 4. 赖国松, 黎波,一种方便检测葡萄糖的非酶电化学生物传感方法,专利号:ZL201710654268.0,授权公告日:20190614

 5. 赖国松, 黎波, 胡胜利, 一种用于非诊断目的的检测肿瘤标志物的比色免疫分析方法,专利号:ZL201611013558.9,授权公告日:20180622

 6. 赖国松,刘顺,张海丽,俞爱民,一种快速检测氯霉素的电化学适配体传感器,专利号:ZL201610506537.4,授权公告日:20181030


主要荣誉及获奖

 1. 楚天学者计划特聘教授,2021年

 2. 中国化学会高级会员,2021年

 3. 湖北师范大学科研先锋之星,2019年

 4. 黄石市第四届自然科学优秀学术成果一等奖,2017年

 5. 江苏省科学技术一等奖(5/10),2017年

 6. 湖北省自然科学优秀学术成果二等奖,2016年

 7. 黄石市五一劳动奖章,2016年

 8. 楚天学者计划楚天学子,2015年

 9. 湖北师范大学优秀教师,2014年

 10. 湖北省自然科学二等奖(4/5),2012年


欢迎对生化分析及生物传感研究感兴趣的研究生和高年级本科生加入本人研究组!


 (Updated: 10 May 2022)