丁鑫

|  个人简介

丁鑫，博士，讲师，硕士生导师，中共党员。1996年2月出生，内蒙古通辽人。2017年6月本科毕业于内蒙古民族大学化学专业，2020年6月硕士毕业于内蒙古民族大学（东北师范大学联合培养）物理化学专业，2023年6月博士毕业于武汉科技大学（武汉大学联合培养）化学工程与技术专业，师从国家杰青刘义教授。2023年9月至今在湖北师范大学化学化工学院工作。

主要从事无机化学教学与生物纳米材料、有机小分子靶点、聚合物胶束和功能性水凝胶的合成，及其在肿瘤的转移/治疗、肾脏/肝脏缺血/再灌注损伤以及呼吸道感染中的应用研究。在Chemical Engineering Journal、Acta Biomaterialia、Advanced Healthcare Materials、ACS Applied Materials & Interfaces等国际刊物上发表SCI收录科研论文20余篇。

|  教学及人才培养

1. 主讲《无机化学》《无机及分析化学》和《无机化学实验》本科生课程

2. 承担本科生学位论文指导工作

3. 担任无机化学学科硕士生导师

 |  主要科研课题

1. 主持：湖北师范大学高层次人才引进科研资助项目(HS2023RC078)

2. 主持：湖北师范大学污染物分子与资源技术湖北省重点实验室资助项目(PA230213)

|  代表性论文论著 

1. Si-Yuan Hu, Xin Ding*, Yan-Jun Hu* et al. Synergistic nano-bioeffects: Dual impact of bisphenol-derived carbon dots on environmental health and antimicrobial therapy. Chemical Engineering Journal 2025, 518: 164871. (中科院一区，TOP期刊，IF: 13.2)

2. Jia-Yu Li¹, Xin Hu¹, Xin Ding*, Yan-Jun Hu* et al. Molecular mechanism of the enhancing of AIE effect by human serum albumin. Sensors & Actuators B. Chemical 2025,440: 137935. (中科院一区，TOP期刊，IF: 7.7)

3. Xin Ding, Yanjun Hu* et al. Construction of polydopamine nanomedicine for dual inhibition and degradation of histone deacetylases in cancer cells. International Journal of Biological Macromolecules 2025, 313, 144340. (中科院二区，TOP期刊，IF: 8.5)

4. Si-Yuan Hu¹, Wen Lin¹, Xin Ding*, Yan-Jun Hu* et al. Molecular mechanism of enhancing antitumor activity through the interaction between monosaccharides and human serum albumin. Analytical and Bioanalytical Chemistry 2025, 417, 251–263. (中科院二区，IF: 3.8)

5. Xiang Wang, Xin Ding*, Yan-Jun Hu* et al. Regulator of oxidative balance: research progress of nanozymes in ROS-related diseases. Materials Today Chemistry 2025, 44, 102540. (中科院二区，TOP期刊，IF: 6.7)

6. Xing Lu, Xin Ding* et al. A curcumin-based HDACs inhibitor for targeted sonodynamic therapy of breast cancer. International Journal of Biological Macromolecules 2025, 287, 138616. (中科院二区，TOP期刊，IF: 7.7)

7. Jia-Yu Li¹, Xin Hu¹, Xin Ding*, Yan-Jun Hu* et al. The effect of electron-withdrawing groups on the binding properties of bisphenol A to DNA: Insights from multi-spectral, electrochemical, and molecular docking. Journal of Molecular Structure 2025, 1322, 140714. (中科院二区，IF: 4.7)

8. Xin Ding, Yi Liu* et al. Modulation of Macrophage Polarity with Carboxymethyl Chitin Gated Hollow Mesoporous Silica Nanoparticles for Elevating Anti-tumor Chemotherapy. International Journal of Biological Macromolecules 2024, 261: 129761. (中科院一区，TOP期刊，IF: 7.7)

9. Xin Ding, Yi Liu* et al. Modulation of Macrophage Polarity with Carboxymethyl Chitin Gated Hollow Mesoporous Silica Nanoparticles for Elevating Anti-tumor Chemotherapy. International Journal of Biological Macromolecules 2024, 261: 129761. DOI: 10.1016/j.ijbiomac.2024.129761 (中科院一区，TOP期刊，IF: 7.7)

10. Ying-Shuang Ao, Xin Ding*, Yan-Jun Hu* et al. Typical Endocrine Disruptors Diethylstilbestrol and Its Analogues Non-Covalently Bind to Human Serum Albumin. Journal of Molecular Structure 2024, 1311: 138409. (中科院二区，IF: 4.0)

11. Xin Ding, Yi Liu∗et al. NIR-II-triggered Photothermal Therapy with Au@PDA/PEG-PI for Targeted Downregulation of PSMA in Prostate Cancer. Acta Biomaterialia 2023 (157) 487-499. (中科院一区，TOP期刊，IF: 10.633)

12. Xin Ding, Yi Liu* et al. A Dual Heat Shock Protein Down-Regulation Strategy using PDA/Cu/ICG/R Controlled by NIR “Switch” Enhances Mild-Photothermal Therapy Effect. Advanced Healthcare Materials, 2023, 2300929. (中科院一区，TOP期刊，IF: 11.092)

13. Xin Ding, Yi Liu* et al. Superoxide Dismutase-Like Regulated Fe/ppa@PDA/B for Synergistically Targeting Ferroptosis/Apoptosis to Enhance Anti-Tumor Efficacy. Advanced Healthcare Materials, 2023, 2301824. (中科院一区，TOP期刊，IF: 11.092)

14. Xin Ding, Yi Liu* et al. Multifunction in One Nanoparticle for Anticancer Therapy: Bowl-Shaped Au@PDA Yolk-Shell NPs. ACS Applied Materials & Interfaces 2022, 14, 24, 27733-27742. DOI: 10.1021/acsami.2c07671 (中科院一区，TOP期刊，IF: 10.383)

15. Yu Zhang¹, Xin Ding¹, Yi Liu* et al. Targeted Recruitment and Degradation of Estrogen Receptor α by Photothermal Polydopamine Nanoparticles for Breast Tumor Ablation. Advanced Healthcare Materials 2022, 2200960. (中科院一区，TOP期刊，IF: 11.092)

|  主要荣誉及获奖 

1. 青年教师讲课比赛理工组一等奖，湖北师范大学，2025.6

(更新时间：2025年9月10日)